KLE Academy of Higher Education and Research (Deemed-to-be-University)
J N Medical College, Belgaum, Karnataka, India
Department of Respiratory Medicine
Research Projects
Ongoing
| Sl No | Principal Investigator | Co-Principal Investigator | Title of the Project | Funding Agency | Duration (From-To) | Clinical Trial Registration Details if any | Status |
| 1 | Dr. Jyothi Hattiholi | – | A Phase 3 , Multicentre, Randomised, Double-blind, Chronic-dosing, Parallel-group, Placebo-controlled Study to Evaluate the Efficacy and Safety of Two Dose Regimens of MEDI13506 in Participants with Symptomatic Chronic Obstructive Pulmonary Diseas (COPD) with a History of COPD Exacerbations (OBERON) | AstraZeneca | – | – | on going |
| 2 | Dr. Jyothi Hattiholi | – | A Randomized, Double-Blind, Double Dummy, Parallel Group, Multicentre 24 to 52 Week Veriable Length Study to Assess the Efficacy and Safety of Budesonide, Glycopyrronium, and Formoterol Fumarate Meterd Dose Inhaler (MDI) Relative to Budesonide and Formoterol Fumarate MDI and Symbicort Pressurized MDI in Adult and Adolescent Participants with Inadequately Controlled Asthma (KALOS) | AstraZeneca | – | – | on going |
| 3 | Dr. Jyothi Hattiholi | – | Prospective, multi-centre, open-label, single-arm, clinical study to evaluate safety and efficacy of OmaliRelTM in patients with moderate to severe persistent asthma. | Reliance Life Sciences | – | – | on going |
| 4 | Dr. Jyothi Hattiholi | – | Randomized double – Blind , Placebo Controlled , parallel-group Phase III study to evaluate the safety and tolerability of SAR440340/REGN3500/itepekimab (anti-IL-33 mAb) in patients with moderate-to-severe chronic Obstructive Pulmonary Disease (COPD) |
Sanofi | – | – | on going |
| 5 | Dr. Jyothi Hattiholi | – | A Phase III, multicentre, randomised, double-blind, chronic dosing, parallel group, placebo controlled extensions. Study to evaluate the long term efficacy and safety of Tozorakimab in participants with Chronic Obstructive Pulmonary Disease (COPD) with a history of exacerbations ( PROSPERO) | AstraZeneca | – | – | on going |
| 6 | Dr Gautam S | – | A Phase 3, multicenter, randomized, double-blind, 24-week study of the clinical and antiviral effect of S-217622 compared with placebo in non-hospitalized participants with COVID-19 |
Shionogi | – | – | on going |
| 7 | Dr. Jyothi Hattiholi | Protocol Title A Randomized, Single-dose, Double-blind, Double-dummy, Placebo and Active Controlled, Crossover Design Study Using Bronchoprovocation to Evaluate the Pharmacodynamic Equivalence of the Test and Reference Metered Dose Inhalers (MDIs) Containing Albuterol Sulfate in Adult Patients with Stable Mild Asthma. | Intech Biopharm Ltd. | – | – | on going | |
| 8 | Dr. Jyothi Hattiholi | Reference: A Phase 3, 24-Week, Randomized, Double-Blind, Placebo-Controlled, Parallel-Arm Efficacy and Safety Study with Open-label Extension of BLU-5937 in Adult Participants with Refractory Chronic Cough Including Unexplained Chronic Cough (CALM-2). |
Bellus health Inc | – | – | on going |
International – Completed
| Sl No | Principal Investigator | Co-Principal Investigator | Title of the Project | Funding Agency | Duration (From-To) | Clinical Trial Registration Details if any | Status |
| 1 | Dr. M.V.Jali, Dr. Vinay Mahishale | Bidirectional screening of diabetes Mellitus and tuberculosis |
1) Govt of India. 2) WHO. 3) WDF. 4) International Union against Tuberculsosis and lung diseases. |
Jan 2012 to Sept 2012 | — | Completed |
Industry Sponsored Clinical Trials – Completed
| Sl No | Principal Investigator | Co-Principal Investigator | Title of the Project | Funding Agency | Duration (From-To) | Clinical Trial Registration Details if any | Status |
| 1 | Dr. Vinay Mahishale | Roflimulast in COPD |
Glenmark |
Jan 2013 to June 2013 | — | Completed |
Completed
| Sl No | Research Scholar | Guide | Co-Guide | Title of the Thesis | Duration (From-To) |
| 1 | Dr. Renu Pattenshetty | Dr. G. S. Gaude | Effect of multimodality chest physiotherapy on the rate recovery and prevention of complications in patients with mechanical ventilation – a prospective study in medical and surgical intensive care units. | 2007-2008 | |
| 2 | Dr. Ravi Saudatti | Dr. G. S. Gaude | Comparative study of postural correction and respiratory muscle training, and only respiratory muscle training in patients with chronic obstructive pulmonary diseases. | 2007-2008 |